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A missing piece of the puzzle: Atg11 functions as a scaffold to activate Atg1 for selective autophagy

The mechanism regulating Atg1 kinase activity for the initiation of selective macroautophagy (hereafter autophagy) under nutrient-rich conditions has been a long-standing question. Canonically in yeast, nutrient starvation or rapamycin treatment repress TOR complex 1 and stimulate the Atg1 complex (...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Delorme-Axford, Elizabeth, Klionsky, Daniel J
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4835187/
https://ncbi.nlm.nih.gov/pubmed/26566077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1116672
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