Mycobacterium PPE31 Contributes to Host Cell Death

Genome scale mutagenesis identifies many genes required for mycobacterial infectivity and survival, but their contributions and mechanisms of action within the host are poorly understood. Using CRISPR interference, we created a knockdown of ppe31(Mm) gene in Mycobacterium marinum (M. marinum), which...

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Vydáno v:Front Cell Infect Microbiol
Hlavní autoři: Feng, Siyuan, Hong, Zhongsi, Zhang, Guoliang, Li, Jiachen, Tian, Guo-Bao, Zhou, Haibo, Huang, Xi
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Cellular and Infection Microbiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8078103/
https://ncbi.nlm.nih.gov/pubmed/33928042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2021.629836
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