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Mycobacterium PPE31 Contributes to Host Cell Death

Genome scale mutagenesis identifies many genes required for mycobacterial infectivity and survival, but their contributions and mechanisms of action within the host are poorly understood. Using CRISPR interference, we created a knockdown of ppe31(Mm) gene in Mycobacterium marinum (M. marinum), which...

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Bibliografiske detaljer
Udgivet i:Front Cell Infect Microbiol
Main Authors: Feng, Siyuan, Hong, Zhongsi, Zhang, Guoliang, Li, Jiachen, Tian, Guo-Bao, Zhou, Haibo, Huang, Xi
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8078103/
https://ncbi.nlm.nih.gov/pubmed/33928042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2021.629836
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