Whole-genome sequencing of phenotypically distinct inflammatory breast cancers reveals similar genomic alterations to non-inflammatory breast cancers

BACKGROUND: Inflammatory breast cancer (IBC) has a highly invasive and metastatic phenotype. However, little is known about its genetic drivers. To address this, we report the largest cohort of whole-genome sequencing (WGS) of IBC cases. METHODS: We performed WGS of 20 IBC samples and paired normal...

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Bibliografiske detaljer
Udgivet i:Genome Med
Main Authors: Li, Xiaotong, Kumar, Sushant, Harmanci, Arif, Li, Shantao, Kitchen, Robert R., Zhang, Yan, Wali, Vikram B., Reddy, Sangeetha M., Woodward, Wendy A., Reuben, James M., Rozowsky, Joel, Hatzis, Christos, Ueno, Naoto T., Krishnamurthy, Savitri, Pusztai, Lajos, Gerstein, Mark
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8077918/
https://ncbi.nlm.nih.gov/pubmed/33902690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-021-00879-x
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