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CRISPR/Cas9 mutagenesis reveals a role for ABCB1 in gut immune responses to Vibrio diazotrophicus in sea urchin larvae

The ABC transporter ABCB1 plays an important role in the disposition of xenobiotics. Embryos of most species express high levels of this transporter in early development as a protective mechanism, but its native substrates are not known. Here, we used larvae of the sea urchin Strongylocentrotus purp...

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Bibliografske podrobnosti
izdano v:J Exp Biol
Main Authors: Fleming, Travis J., Schrankel, Catherine S., Vyas, Himanshu, Rosenblatt, Hannah D., Hamdoun, Amro
Format: Artigo
Jezik:Inglês
Izdano: The Company of Biologists Ltd 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8077557/
https://ncbi.nlm.nih.gov/pubmed/33653719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jeb.232272
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