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CRISPR/Cas9 mutagenesis reveals a role for ABCB1 in gut immune responses to Vibrio diazotrophicus in sea urchin larvae

The ABC transporter ABCB1 plays an important role in the disposition of xenobiotics. Embryos of most species express high levels of this transporter in early development as a protective mechanism, but its native substrates are not known. Here, we used larvae of the sea urchin Strongylocentrotus purp...

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Detalhes bibliográficos
Publicado no:J Exp Biol
Main Authors: Fleming, Travis J., Schrankel, Catherine S., Vyas, Himanshu, Rosenblatt, Hannah D., Hamdoun, Amro
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8077557/
https://ncbi.nlm.nih.gov/pubmed/33653719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jeb.232272
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