STARTRAC analyses of scRNAseq data from tumor models reveal T cell dynamics and therapeutic targets

Single-cell RNA sequencing is a powerful tool to examine cellular heterogeneity, novel markers and target genes, and therapeutic mechanisms in human cancers and animal models. Here, we analyzed single-cell RNA sequencing data of T cells obtained from multiple mouse tumor models by PCA-based subclust...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Bhatt, Dev, Kang, Boxi, Sawant, Deepali, Zheng, Liangtao, Perez, Kristy, Huang, Zhiyu, Sekirov, Laura, Wolak, Dan, Huang, Julie Y., Liu, Xian, DeVoss, Jason, Manzanillo, Paolo S., Pierce, Nathan, Zhang, Zemin, Symons, Antony, Ouyang, Wenjun
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2021
Assuntos:
Technical Advances and Resources
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8077174/
https://ncbi.nlm.nih.gov/pubmed/33900375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20201329
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