Neuroprotective Effects of Oxymatrine on PI3K/Akt/mTOR Pathway After Hypoxic-Ischemic Brain Damage in Neonatal Rats

Oxymatrine (OMT), a quinolizidine alkaloid extracted from traditional Chinese herb Sophora flavescens Ait, has drawn attention because of its beneficial bioactivities against hypoxic–ischemic brain damage (HIBD). However, the underlying molecular mechanism remains unclear. In this study, we determin...

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Bibliographic Details
Published in:Front Pharmacol
Main Authors: Wei, Wei, Lu, Min, Lan, Xiao-bing, Liu, Ning, Su, Wei-ke, Dushkin, Alexandr V., Yu, Jian-qiang
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8077028/
https://ncbi.nlm.nih.gov/pubmed/33927621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.642415
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