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Neuroprotective Effects of Oxymatrine on PI3K/Akt/mTOR Pathway After Hypoxic-Ischemic Brain Damage in Neonatal Rats

Oxymatrine (OMT), a quinolizidine alkaloid extracted from traditional Chinese herb Sophora flavescens Ait, has drawn attention because of its beneficial bioactivities against hypoxic–ischemic brain damage (HIBD). However, the underlying molecular mechanism remains unclear. In this study, we determin...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Wei, Wei, Lu, Min, Lan, Xiao-bing, Liu, Ning, Su, Wei-ke, Dushkin, Alexandr V., Yu, Jian-qiang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8077028/
https://ncbi.nlm.nih.gov/pubmed/33927621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.642415
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