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Bioinformatics methods for identification of amyloidogenic peptides show robustness to misannotated training data
Several disorders are related to amyloid aggregation of proteins, for example Alzheimer’s or Parkinson’s diseases. Amyloid proteins form fibrils of aggregated beta structures. This is preceded by formation of oligomers—the most cytotoxic species. Determining amyloidogenicity is tedious and costly. T...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8076271/ https://ncbi.nlm.nih.gov/pubmed/33903613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-86530-6 |
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