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Amyloidogenic motifs revealed by n-gram analysis

Amyloids are proteins associated with several clinical disorders, including Alzheimer’s, and Creutzfeldt-Jakob’s. Despite their diversity, all amyloid proteins can undergo aggregation initiated by short segments called hot spots. To find the patterns defining the hot spots, we trained predictors of...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Burdukiewicz, Michał, Sobczyk, Piotr, Rödiger, Stefan, Duda-Madej, Anna, Mackiewicz, Paweł, Kotulska, Małgorzata
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5636826/
https://ncbi.nlm.nih.gov/pubmed/29021608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13210-9
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