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Prognostic significance of interleukin-17A-producing colorectal tumour antigen-specific T cells

BACKGROUND: The T cell cytokine profile is a key prognostic indicator of post-surgical outcome for colorectal cancer (CRC). Whilst T(H)1 (IFN-γ(+)) cell-mediated responses generated in CRC are well documented and are associated with improved survival, antigen-specific T(H)17 (IL-17A(+)) responses ha...

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Bibliografski detalji
Izdano u:Br J Cancer
Glavni autori: Thomson, Amanda, Bento, Diana F. Costa, Scurr, Martin J., Smart, Kathryn, Somerville, Michelle S., Keita, Åsa V., Gallimore, Awen, Godkin, Andrew
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8076199/
https://ncbi.nlm.nih.gov/pubmed/33674735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-021-01283-3
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