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Protein-induced Conformational Change in Glycans Decreases Resolution of Glycoproteins in Hydrophilic Interaction Liquid Chromatography
An understanding of why hydrophilic interaction liquid chromatography (HILIC) gives higher resolution for glycans than for glycoproteins would facilitate column improvements. Separations of the glycoforms of ribonuclease B compared to its released glycans were studied using a commercial HILIC column...
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| Veröffentlicht in: | J Sep Sci |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8076065/ https://ncbi.nlm.nih.gov/pubmed/33682335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jssc.202001242 |
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