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Protein-induced Conformational Change in Glycans Decreases Resolution of Glycoproteins in Hydrophilic Interaction Liquid Chromatography
An understanding of why hydrophilic interaction liquid chromatography (HILIC) gives higher resolution for glycans than for glycoproteins would facilitate column improvements. Separations of the glycoforms of ribonuclease B compared to its released glycans were studied using a commercial HILIC column...
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| Publicado no: | J Sep Sci |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8076065/ https://ncbi.nlm.nih.gov/pubmed/33682335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jssc.202001242 |
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