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Plectin ensures intestinal epithelial integrity and protects colon against colitis

Plectin, a highly versatile cytolinker protein, provides tissues with mechanical stability through the integration of intermediate filaments (IFs) with cell junctions. Here, we hypothesize that plectin-controlled cytoarchitecture is a critical determinant of the intestinal barrier function and homeo...

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Veröffentlicht in:Mucosal Immunol
Hauptverfasser: Krausova, Alzbeta, Buresova, Petra, Sarnova, Lenka, Oyman-Eyrilmez, Gizem, Skarda, Jozef, Wohl, Pavel, Bajer, Lukas, Sticova, Eva, Bartonova, Lenka, Pacha, Jiri, Koubkova, Gizela, Prochazka, Jan, Spörrer, Marina, Dürrbeck, Christopher, Stehlikova, Zuzana, Vit, Martin, Ziolkowska, Natalia, Sedlacek, Radislav, Jirak, Daniel, Kverka, Miloslav, Wiche, Gerhard, Fabry, Ben, Korinek, Vladimir, Gregor, Martin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group US 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8076044/
https://ncbi.nlm.nih.gov/pubmed/33674761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41385-021-00380-z
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