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Pharmacokinetics of 10-Hydroxy Mesaconitine in Rat Plasma by Ultra-Performance Liquid Chromatography-Tandem Quadrupole Mass Spectrometry

Mesaconitine is the predominant active ingredient in Aconitum carmichaelii Debx. The compound 10-hydroxy mesaconitine is one known metabolite of mesaconitine and is toxic. In order to better understand its pharmacokinetics, UPLC-MS/MS was used in this paper to measure the concentration of 10-hydroxy...

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Detalhes bibliográficos
Publicado no:J Anal Methods Chem
Main Authors: Yang, Jinzhao, Zeng, Guowu, Ma, Jianshe, Wang, Xianqin, Zhou, Quan
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8075697/
https://ncbi.nlm.nih.gov/pubmed/33959404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/6640184
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