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High-throughput screening of compound neurotoxicity using 3D-cultured neural stem cells on a 384-pillar plate

Assessing the neurotoxicity of test chemicals has typically been performed using two-dimensionally (2D) cultured neuronal cell monolayers and animal models. The in vitro 2D cell models are simple and straightforward compared to animal models, which have the disadvantage of being relatively low throu...

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Detalhes bibliográficos
Publicado no:Curr Protoc
Main Authors: Kang, Soo-Yeon, Joshi, Pranav, Lee, Moo-Yeal
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8075006/
https://ncbi.nlm.nih.gov/pubmed/33887124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpz1.107
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