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High-throughput assessment of mechanistic toxicity of chemicals in miniaturized 3D cell culture
High-content imaging (HCI) assays on two-dimensional (2D) cell cultures often don’t represent in vivo characteristics accurately, thus reducing the predictability of drug toxicity/efficacy in vivo. On the other hand, conventional 3D cell cultures are relatively low throughput and possess difficulty...
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| 發表在: | Curr Protoc Toxicol |
|---|---|
| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6347521/ https://ncbi.nlm.nih.gov/pubmed/30387930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cptx.66 |
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