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High-throughput assessment of mechanistic toxicity of chemicals in miniaturized 3D cell culture

High-content imaging (HCI) assays on two-dimensional (2D) cell cultures often don’t represent in vivo characteristics accurately, thus reducing the predictability of drug toxicity/efficacy in vivo. On the other hand, conventional 3D cell cultures are relatively low throughput and possess difficulty...

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Bibliografske podrobnosti
izdano v:Curr Protoc Toxicol
Main Authors: Joshi, Pranav, Kang, Soo-Yeon, Datar, Akshata, Lee, Moo-Yeal
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6347521/
https://ncbi.nlm.nih.gov/pubmed/30387930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cptx.66
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