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De novo design of modular and tunable protein biosensors

Naturally occurring protein switches have been repurposed for developing novel biosensors and reporters for cellular and clinical applications(1), but the number of such switches is limited, and engineering them is often challenging as each is different. Here, we show that a very general class of pr...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Quijano-Rubio, Alfredo, Yeh, Hsien-Wei, Park, Jooyoung, Lee, Hansol, Langan, Robert A., Boyken, Scott E., Lajoie, Marc J., Cao, Longxing, Chow, Cameron M., Miranda, Marcos C., Wi, Jimin, Hong, Hyo Jeong, Stewart, Lance, Oh, Byung-Ha, Baker, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8074680/
https://ncbi.nlm.nih.gov/pubmed/33503651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-021-03258-z
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