Down-Regulation of the Proteoglycan Decorin Fills in the Tumor-Promoting Phenotype of Ionizing Radiation-Induced Senescent Human Breast Stromal Fibroblasts

SIMPLE SUMMARY: Ionizing radiation (a typical remedy for breast cancer) results in the premature senescence of the adjacent to the neoplastic cells stromal fibroblasts. Here, we showed that these senescent fibroblasts are characterized by the down-regulation of the small leucine-rich proteoglycan de...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Mavrogonatou, Eleni, Papadopoulou, Adamantia, Fotopoulou, Asimina, Tsimelis, Stathis, Bassiony, Heba, Yiacoumettis, Andreas M., Panagiotou, Petros N., Pratsinis, Harris, Kletsas, Dimitris
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8074608/
https://ncbi.nlm.nih.gov/pubmed/33924197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13081987
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