Mitochondrial complex I abnormalities is associated with tau and clinical symptoms in mild Alzheimer’s disease

BACKGROUND: Mitochondrial electron transport chain abnormalities have been reported in postmortem pathological specimens of Alzheimer’s disease (AD). However, it remains unclear how amyloid and tau are associated with mitochondrial dysfunction in vivo. The purpose of this study is to assess the loca...

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Detalhes bibliográficos
Publicado no:Mol Neurodegener
Main Authors: Terada, Tatsuhiro, Therriault, Joseph, Kang, Min Su Peter, Savard, Melissa, Pascoal, Tharick Ali, Lussier, Firoza, Tissot, Cecile, Wang, Yi-Ting, Benedet, Andrea, Matsudaira, Takashi, Bunai, Tomoyasu, Obi, Tomokazu, Tsukada, Hideo, Ouchi, Yasuomi, Rosa-Neto, Pedro
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8074456/
https://ncbi.nlm.nih.gov/pubmed/33902654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-021-00448-1
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