Targeting lactate dehydrogenase a improves radiotherapy efficacy in non-small cell lung cancer: from bedside to bench

BACKGROUND: Lactate dehydrogenase A (LDHA) is overexpressed and associated with poor prognosis in many kinds of cancer. In the current study, we evaluated the prognostic value of LDHA expression in non-small cell lung cancer (NSCLC), and tested whether LDHA inhibition might improve radiotherapy effi...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Yang, Yang, Chong, Yu, Chen, Mengyuan, Dai, Wumin, Zhou, Xia, Ji, Yongling, Qiu, Guoqin, Du, Xianghui
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8074241/
https://ncbi.nlm.nih.gov/pubmed/33902615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-021-02825-2
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