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Accurate Quantification of AAV Vector Genomes by Quantitative PCR

The ability to accurately determine the dose of an adeno-associated viral (AAV) therapeutic vector is critical to the gene therapy process. Quantitative PCR (qPCR) is one of the common methods to quantify the AAV vector titre, but different variables can lead to inconsistent results. The aim of this...

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Pubblicato in:Genes (Basel)
Autori principali: Martinez-Fernandez de la Camara, Cristina, McClements, Michelle E., MacLaren, Robert E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8074223/
https://ncbi.nlm.nih.gov/pubmed/33921790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes12040601
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