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Accurate Quantification of AAV Vector Genomes by Quantitative PCR

The ability to accurately determine the dose of an adeno-associated viral (AAV) therapeutic vector is critical to the gene therapy process. Quantitative PCR (qPCR) is one of the common methods to quantify the AAV vector titre, but different variables can lead to inconsistent results. The aim of this...

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Bibliografiske detaljer
Udgivet i:Genes (Basel)
Main Authors: Martinez-Fernandez de la Camara, Cristina, McClements, Michelle E., MacLaren, Robert E.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8074223/
https://ncbi.nlm.nih.gov/pubmed/33921790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes12040601
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