Fluorochloridone induces autophagy in TM4 Sertoli cells: involvement of ROS-mediated AKT-mTOR signaling pathway

BACKGROUND: Fluorochloridone (FLC), a selective pyrrolidone herbicide, has been recognized as a potential endocrine disruptor and reported to induce male reproductive toxicity, but the underlying mechanism is unclear. The aim of this study was to investigate the mechanism of FLC-induced reproductive...

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Gepubliceerd in:Reprod Biol Endocrinol
Hoofdauteurs: Ni, Zhijing, Sun, Weiqi, Li, Rui, Yang, Mingjun, Zhang, Fen, Chang, Xiuli, Li, Weihua, Zhou, Zhijun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2021
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Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8073911/
https://ncbi.nlm.nih.gov/pubmed/33902598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12958-021-00739-8
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