Spray-Dried Formulation of Epicertin, a Recombinant Cholera Toxin B Subunit Variant That Induces Mucosal Healing

Epicertin (EPT) is a recombinant variant of the cholera toxin B subunit, modified with a C-terminal KDEL endoplasmic reticulum retention motif. EPT has therapeutic potential for ulcerative colitis treatment. Previously, orally administered EPT demonstrated colon epithelial repair activity in dextran...

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Bibliografiske detaljer
Udgivet i:Pharmaceutics
Main Authors: Reeves, Micaela A., Royal, Joshua M., Morris, David A., Jurkiewicz, Jessica M., Matoba, Nobuyuki, Hamorsky, Krystal T.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8073836/
https://ncbi.nlm.nih.gov/pubmed/33919585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13040576
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