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Estrogen Decreases Cytoskeletal Organization by Forming an ERα/SHP2/c-Src Complex in Osteoclasts to Protect against Ovariectomy-Induced Bone Loss in Mice

Loss of ovarian function is closely related to estrogen (E(2)) deficiency, which is responsible for increased osteoclast (OC) differentiation and activity. We aimed to investigate the action mechanism of E(2) to decrease bone resorption in OCs to protect from ovariectomy (OVX)-induced bone loss in m...

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Publicat a:Antioxidants (Basel)
Autors principals: Park, Hyun-Jung, Gholam-Zadeh, Malihatosadat, Yoon, Sun-Young, Suh, Jae-Hee, Choi, Hye-Seon
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8073670/
https://ncbi.nlm.nih.gov/pubmed/33920630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox10040619
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