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Estrogen Decreases Cytoskeletal Organization by Forming an ERα/SHP2/c-Src Complex in Osteoclasts to Protect against Ovariectomy-Induced Bone Loss in Mice

Loss of ovarian function is closely related to estrogen (E(2)) deficiency, which is responsible for increased osteoclast (OC) differentiation and activity. We aimed to investigate the action mechanism of E(2) to decrease bone resorption in OCs to protect from ovariectomy (OVX)-induced bone loss in m...

詳細記述

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書誌詳細
出版年:Antioxidants (Basel)
主要な著者: Park, Hyun-Jung, Gholam-Zadeh, Malihatosadat, Yoon, Sun-Young, Suh, Jae-Hee, Choi, Hye-Seon
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8073670/
https://ncbi.nlm.nih.gov/pubmed/33920630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox10040619
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