BK(Ca) Channel Inhibition by Peripheral Nerve Injury Is Restored by the Xanthine Derivative KMUP-1 in Dorsal Root Ganglia

This study explored whether KMUP-1 improved chronic constriction injury (CCI)-induced BK(Ca) current inhibition in dorsal root ganglion (DRG) neurons. Rats were randomly assigned to four groups: sham, sham + KMUP-1, CCI, and CCI + KMUP-1 (5 mg/kg/day, i.p.). DRG neuronal cells (L4–L6) were isolated...

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Publicado no:Cells
Main Authors: Cheng, Kuang-I, Yang, Kan-Ting, Kung, Chien-Lun, Cheng, Yu-Chi, Yeh, Jwu-Lai, Dai, Zen-Kong, Wu, Bin-Nan
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8073306/
https://ncbi.nlm.nih.gov/pubmed/33923953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10040949
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