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AP-1 and NF-κB synergize to transcriptionally activate latent HIV upon T-cell receptor activation

Latent HIV-1 proviruses are capable of reactivating productive lytic infection, but the precise molecular mechanisms underlying emergence from latency are poorly understood. In this study, we determined the contribution of the transcription factors NF-κB, NFAT, and AP-1 in the reactivation of latent...

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Publicado en:FEBS Lett
Autores principales: Hokello, Joseph, Sharma, Adhikarimayum Lakhikumar, Tyagi, Mudit
Formato: Artigo
Lenguaje:Inglês
Publicado: 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8073299/
https://ncbi.nlm.nih.gov/pubmed/33421101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.14033
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