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AP-1 and NF-κB synergize to transcriptionally activate latent HIV upon T-cell receptor activation

Latent HIV-1 proviruses are capable of reactivating productive lytic infection, but the precise molecular mechanisms underlying emergence from latency are poorly understood. In this study, we determined the contribution of the transcription factors NF-κB, NFAT, and AP-1 in the reactivation of latent...

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Dades bibliogràfiques
Publicat a:FEBS Lett
Autors principals: Hokello, Joseph, Sharma, Adhikarimayum Lakhikumar, Tyagi, Mudit
Format: Artigo
Idioma:Inglês
Publicat: 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8073299/
https://ncbi.nlm.nih.gov/pubmed/33421101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.14033
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