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Fully Automated Synthesis of Novel TSPO PET Imaging Ligand [(18)F]Fluoroethyltemazepam

Introduction: Benzodiazepines, including temazepam are described as TSPO antagonists. In fact, TSPO was initially described as a peripheral benzodiazepine receptor (PBR) with a secondary binding site for diazepam. TSPO is a potential imaging target of neuroinflammation because there is an amplificat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Molecules
Hauptverfasser: Fiorenza, Dario, Nicolai, Emanuele, Cavaliere, Carlo, Fiorino, Ferdinando, Esposito, Giovanna, Salvatore, Marco
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8073130/
https://ncbi.nlm.nih.gov/pubmed/33921765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26082372
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