GMP-compliant fully automated radiosynthesis of [(18)F]FEPPA for PET/MRI imaging of regional brain TSPO expression

BACKGROUND: Expression of translocator protein (TSPO) on the outer mitochondrial membrane of activated microglia is strongly associated with neuroinflammation. The second-generation PET ligand [(18)F]FEPPA specifically binds TSPO to enable in vivo visualization and quantification of neuroinflammatio...

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Udgivet i:EJNMMI Res
Main Authors: Chang, Chi-Wei, Chiu, Chuang-Hsin, Lin, Ming-Hsien, Wu, Hung-Ming, Yu, Tsung-Hsun, Wang, Pao-Yeh, Kuo, Yu-Yeh, Huang, Ya-Yao, Shiue, Chyng-Yann, Huang, Wen-Sheng, Yeh, Skye Hsin-Hsien
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2021
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7966678/
https://ncbi.nlm.nih.gov/pubmed/33725191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-021-00768-9
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