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Predicting Pharmacokinetic Properties of Potential Anticancer Agents via Their Chromatographic Behavior on Different Reversed Phase Materials
The Quantitative Structure-Activity Relationship (QSAR) methodology was used to predict biological properties, i.e., the blood–brain distribution (log BB), fraction unbounded in the brain (f(u,brain)), water-skin permeation (log K(p)), binding to human plasma proteins (log K(a,HSA)), and intestinal...
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| Publicado en: | Int J Mol Sci |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
MDPI
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8072580/ https://ncbi.nlm.nih.gov/pubmed/33923942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22084257 |
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