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Predicting the Blood-Brain Barrier Permeability of New Drug-Like Compounds via HPLC with Various Stationary Phases

The permeation of the blood-brain barrier is a very important consideration for new drug candidate molecules. In this research, the reversed-phase liquid chromatography with different columns (Purosphere RP-18e, IAM.PC.DD2 and Cosmosil Cholester) was used to predict the penetration of the blood-brai...

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Bibliografiska uppgifter
I publikationen:Molecules
Huvudupphovsmän: Janicka, Małgorzata, Sztanke, Małgorzata, Sztanke, Krzysztof
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7037052/
https://ncbi.nlm.nih.gov/pubmed/31979316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25030487
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