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Microfluidic Blood-Brain Barrier Model Provides In Vivo-Like Barrier Properties for Drug Permeability Screening

Efficient delivery of therapeutics across the neuroprotective blood-brain barrier (BBB) remains a formidable challenge for central nervous system drug development. High-fidelity in vitro models of the BBB could facilitate effective early screening of drug candidates targeting the brain. In this stud...

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Detalhes bibliográficos
Publicado no:Biotechnol Bioeng
Main Authors: Wang, Ying I., Abaci, Hasan Erbil, Shuler, Michael L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6650146/
https://ncbi.nlm.nih.gov/pubmed/27399645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.26045
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