Relative oxygen extraction fraction (rOEF) MR imaging reveals higher hypoxia in human epidermal growth factor receptor (EGFR) amplified compared with non-amplified gliomas

PURPOSE: Epidermal growth factor receptor (EGFR) amplification promotes gliomagenesis and is linked to lack of oxygen within the tumor microenvironment. Using hypoxia-sensitive spin-and-gradient echo echo-planar imaging and perfusion MRI, we investigated the influence of EGFR amplification on tissue...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Neuroradiology
मुख्य लेखकों: Oughourlian, Talia C., Yao, Jingwen, Hagiwara, Akifumi, Nathanson, David A., Raymond, Catalina, Pope, Whitney B., Salamon, Noriko, Lai, Albert, Ji, Matthew, Nghiemphu, Phioanh L., Liau, Linda M., Cloughesy, Timothy F., Ellingson, Benjamin M.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2020
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC8071834/
https://ncbi.nlm.nih.gov/pubmed/33106922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00234-020-02585-8
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