Functional and Genetic Landscape of Complement Dysregulation Along the Spectrum of Thrombotic Microangiopathy and its Potential Implications on Clinical Outcomes

INTRODUCTION: The syndromes of thrombotic microangiopathy (TMA) are diverse and represent severe endothelial damage caused by various mechanisms. The complement system plays a major role in a subset of patients with TMA, and its recognition is of clinical importance because it guides choice and dura...

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Detalhes bibliográficos
Publicado no:Kidney Int Rep
Principais autores: Timmermans, Sjoerd A.M.E.G., Damoiseaux, Jan G.M.C., Werion, Alexis, Reutelingsperger, Chris P., Morelle, Johann, van Paassen, Pieter
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Clinical Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8071658/
https://ncbi.nlm.nih.gov/pubmed/33912760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ekir.2021.01.034
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