C5b9 Formation on Endothelial Cells Reflects Complement Defects among Patients with Renal Thrombotic Microangiopathy and Severe Hypertension

Background Severe hypertension can induce thrombotic microangiopathy (TMA) in the renal vasculature, the occurrence of which has been linked to mechanical stress to the endothelium. Complement defects may be the culprit of disease in patients who present with severe renal disease and often progress...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Timmermans, Sjoerd A.M.E.G., Abdul-Hamid, Myrurgia A., Potjewijd, Judith, Theunissen, Ruud O.M.F.I.H., Damoiseaux, Jan G.M.C., Reutelingsperger, Chris P., van Paassen, Pieter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2018
Assuntos:
Clinical Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6065094/
https://ncbi.nlm.nih.gov/pubmed/29858281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2018020184
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