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Computational Design and Development of Benzodioxane-Benzamides as Potent Inhibitors of FtsZ by Exploring the Hydrophobic Subpocket

Multidrug resistant Staphylococcus aureus is a severe threat, responsible for most of the nosocomial infections globally. This resistant strain is associated with a 64% increase in death compared to the antibiotic-susceptible strain. The prokaryotic protein FtsZ and the cell division cycle have been...

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Библиографические подробности
Опубликовано в: :Antibiotics (Basel)
Главные авторы: Straniero, Valentina, Sebastián-Pérez, Victor, Suigo, Lorenzo, Margolin, William, Casiraghi, Andrea, Hrast, Martina, Zanotto, Carlo, Zdovc, Irena, Radaelli, Antonia, Valoti, Ermanno
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2021
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8071314/
https://ncbi.nlm.nih.gov/pubmed/33920895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antibiotics10040442
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