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Targeting Bacterial Cell Division: A Binding Site-Centered Approach to the Most Promising Inhibitors of the Essential Protein FtsZ

Binary fission is the most common mode of bacterial cell division and is mediated by a multiprotein complex denominated the divisome. The constriction of the Z-ring splits the mother bacterial cell into two daughter cells of the same size. The Z-ring is formed by the polymerization of FtsZ, a bacter...

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Detalhes bibliográficos
Publicado no:Antibiotics (Basel)
Main Authors: Casiraghi, Andrea, Suigo, Lorenzo, Valoti, Ermanno, Straniero, Valentina
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7167804/
https://ncbi.nlm.nih.gov/pubmed/32046082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antibiotics9020069
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