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Heme-Mediated Activation of the Nrf2/HO-1 Axis Attenuates Calcification of Valve Interstitial Cells

Calcific aortic valve stenosis (CAVS) is a heart disease characterized by the progressive fibro-calcific remodeling of the aortic valves, an actively regulated process with the involvement of the reactive oxygen species-mediated differentiation of valvular interstitial cells (VICs) into osteoblast-l...

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Dettagli Bibliografici
Pubblicato in:Biomedicines
Autori principali: Balogh, Enikő, Chowdhury, Arpan, Ababneh, Haneen, Csiki, Dávid Máté, Tóth, Andrea, Jeney, Viktória
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8071288/
https://ncbi.nlm.nih.gov/pubmed/33920891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9040427
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