Induction of NLRP3 Inflammasome Activation by Heme in Human Endothelial Cells

Hemolytic or hemorrhagic episodes are often associated with inflammation even when infectious agents are absent suggesting that red blood cells (RBCs) release damage-associated molecular patterns (DAMPs). DAMPs activate immune and nonimmune cells through pattern recognition receptors. Heme, released...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Erdei, Judit, Tóth, Andrea, Balogh, Enikő, Nyakundi, Benard Bogonko, Bányai, Emese, Ryffel, Bernhard, Paragh, György, Cordero, Mario D., Jeney, Viktória
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5883980/
https://ncbi.nlm.nih.gov/pubmed/29743981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/4310816
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