Synergistic Effect of Doxorubicin and siRNA-Mediated Silencing of Mcl-1 Using Cationic Niosomes against 3D MCF-7 Spheroids

Chemotherapy is a vital option for cancer treatment; however, its therapeutic outcomes are limited by dose-dependent toxicity and the occurrence of chemoresistance. siRNAs have emerged as an attractive therapeutic option enabling specific interference with target genes. Combination therapy using che...

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Bibliografiske detaljer
Udgivet i:Pharmaceutics
Main Authors: Pengnam, Supusson, Plianwong, Samarwadee, Patrojanasophon, Prasopchai, Radchatawedchakoon, Widchaya, Yingyongnarongkul, Boon-ek, Opanasopit, Praneet, Charoensuksai, Purin
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8070967/
https://ncbi.nlm.nih.gov/pubmed/33919902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13040550
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