Chitosan Combined with Poly-L-arginine as Efficient, Safe, and Serum-Insensitive Vehicle with RNase Protection Ability for siRNA Delivery

Chitosan (CS) combined with poly-L-arginine (PLA) was formulated and evaluated for its performance to deliver siRNA to HeLa cells expressing enhanced green fluorescent protein (EGFP). Compared with the formulations using single polymer in which the polyplexes were completely formed at the weight rat...

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Autores principales: Plianwong, Samarwadee, Opanasopit, Praneet, Ngawhirunpat, Tanasait, Rojanarata, Theerasak
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3705865/
https://ncbi.nlm.nih.gov/pubmed/23865058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/574136
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