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A Link between Replicative Stress, Lamin Proteins, and Inflammation

Double-stranded breaks (DSB), the most toxic DNA lesions, are either a consequence of cellular metabolism, programmed as in during V(D)J recombination, or induced by anti-tumoral therapies or accidental genotoxic exposure. One origin of DSB sources is replicative stress, a major source of genome ins...

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Main Authors: Willaume, Simon, Rass, Emilie, Fontanilla-Ramirez, Paula, Moussa, Angela, Wanschoor, Paul, Bertrand, Pascale
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8070205/
https://ncbi.nlm.nih.gov/pubmed/33918867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes12040552
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