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Hidden Targets in RAF Signalling Pathways to Block Oncogenic RAS Signalling

Oncogenic RAS (Rat sarcoma) mutations drive more than half of human cancers, and RAS inhibition is the holy grail of oncology. Thirty years of relentless efforts and harsh disappointments have taught us about the intricacies of oncogenic RAS signalling that allow us to now get a pharmacological grip...

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Bibliografische gegevens
Gepubliceerd in:Genes (Basel)
Hoofdauteurs: Nolan, Aoife A., Aboud, Nourhan K., Kolch, Walter, Matallanas, David
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2021
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8070103/
https://ncbi.nlm.nih.gov/pubmed/33920182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes12040553
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