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Chemogenetic Activation of CX3CR1-Expressing Spinal Microglia Using Gq-DREADD Elicits Mechanical Allodynia in Male Mice

It is important to investigate the sex-dependent roles of microglia in pain hypersensitivity as reactive microglia within the spinal dorsal horn (DH) have been reported to be pivotal in neuropathic pain induction in male rodents upon nerve injury. Here, we aimed at determining the role of sex differ...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Saika, Fumihiro, Matsuzaki, Shinsuke, Kishioka, Shiroh, Kiguchi, Norikazu
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8069983/
https://ncbi.nlm.nih.gov/pubmed/33921365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10040874
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