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Divergent Regulation of OCT and MATE Drug Transporters by Cadmium Exposure

Coordinated transcellular transport by the uptake via organic cation transporters (OCTs) in concert with the efflux via multidrug and toxin extrusion proteins (MATEs) is an essential system for hepatic and renal drug disposition. Despite their clinical importance, the regulation of OCTs and MATEs re...

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Détails bibliographiques
Publié dans:Pharmaceutics
Auteurs principaux: Yang, Hong, Zhou, Shiwei, Guo, Dong, Obianom, Obinna N., Li, Qing, Shu, Yan
Format: Artigo
Langue:Inglês
Publié: MDPI 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8069296/
https://ncbi.nlm.nih.gov/pubmed/33924306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13040537
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