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Pyrvinium Treatment Confers Hepatic Metabolic Benefits via β-catenin Downregulation and AMPK Activation
Genetic evidence has indicated that β-catenin plays a vital role in glucose and lipid metabolism. Here, we investigated whether pyrvinium, an anthelmintic agent previously reported as a down-regulator of cellular β-catenin levels, conferred any metabolic advantages in treatment of metabolic disorder...
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| Vydáno v: | Pharmaceutics |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
MDPI
2021
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8001320/ https://ncbi.nlm.nih.gov/pubmed/33806415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13030330 |
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