טוען...

Inhibition of Autophagy at Different Stages by ATG5 Knockdown and Chloroquine Supplementation Enhances Consistent Human Disc Cellular Apoptosis and Senescence Induction rather than Extracellular Matrix Catabolism

The intervertebral disc is the largest avascular organ. Autophagy is an important cell survival mechanism by self-digestion and recycling damaged components under stress, primarily nutrient deprivation. Resident cells would utilize autophagy to cope with the harsh disc environment. Our objective was...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Int J Mol Sci
Main Authors: Ito, Masaaki, Yurube, Takashi, Kanda, Yutaro, Kakiuchi, Yuji, Takeoka, Yoshiki, Takada, Toru, Kuroda, Ryosuke, Kakutani, Kenichiro
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI 2021
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC8069032/
https://ncbi.nlm.nih.gov/pubmed/33921398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22083965
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