Synthesis of Polyanionic C5-Modified 2′-Deoxyuridine and 2′-Deoxycytidine-5′-Triphosphates and Their Properties as Substrates for DNA Polymerases

Modified 2′-deoxyribonucleotide triphosphates (dNTPs) have widespread applications in both existing and emerging biomolecular technologies. For such applications it is an essential requirement that the modified dNTPs be substrates for DNA polymerases. To date very few examples of C5-modified dNTPs b...

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Bibliographic Details
Published in:Molecules
Main Authors: Dutson, Claire, Allen, Esther, Thompson, Mark J., Hedley, Joseph H., Murton, Heather E., Williams, David M.
Format: Artigo
Language:Inglês
Published: MDPI 2021
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8069024/
https://ncbi.nlm.nih.gov/pubmed/33924626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26082250
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