Adsorption of Phenazines Produced by Pseudomonas aeruginosa Using AST-120 Decreases Pyocyanin-Associated Cytotoxicity

AST-120 (Kremezin) is used to treat progressive chronic kidney disease by adsorbing uremic toxin precursors produced by the gut microbiota, such as indole and phenols. Previously, we found that AST-120 decreased drug tolerance and virulence in Escherichia coli by adsorbing indole. Here, we show that...

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Publicado en:Antibiotics (Basel)
Main Authors: Hirakawa, Hidetada, Takita, Ayako, Uchida, Motoyuki, Kaneko, Yuka, Kakishima, Yuto, Tanimoto, Koichi, Kamitani, Wataru, Tomita, Haruyoshi
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2021
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8068879/
https://ncbi.nlm.nih.gov/pubmed/33924459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antibiotics10040434
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